RN Exam Practice
Pharmacological and Parenteral TherapiesQuestion 493 of 2368

A client in the emergency department has chest pain and asks for nitroglycerin. The client states that sildenafil was taken 6 hours ago. What is the nurse's concern?

  1. The combination may cause a dangerous rise in blood pressure.
  2. The combination may cause sudden bradycardia.
  3. The combination may cause a dangerous drop in blood pressure.
  4. The combination may cause rapid potassium loss.
Show answer

Correct answer: The combination may cause a dangerous drop in blood pressure.

A client who took sildenafil in the previous 24 hours should not take nitroglycerin because of severe hypotension.

Source: Nursing Pharmacology, 2nd edition (Open RN, Chippewa Valley Technical College, 2023), Cardiovascular & Renal Systems: ANTIANGINAL – NITRATES. Licensed under CC BY 4.0.

Practice the topic "Pharmacological and Parenteral Therapies"

Questions last reviewed: 18 October 2026