Pharmacological and Parenteral TherapiesQuestion 2312 of 2368

A client receiving spinal morphine has itching, and the provider orders diphenhydramine. What should the nurse monitor for with this medication?

  1. Hypertension
  2. Hyperglycemia
  3. Sedative effects
  4. Severe withdrawal
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Correct answer: Sedative effects

Antihistamines used for pruritus can add sedation, which matters in a client already receiving an opioid.

Source: Nursing Fundamentals, 2nd edition (Open RN, Chippewa Valley Technical College, 2024), Comfort: PRURITUS. Licensed under CC BY 4.0.

Practice the topic "Pharmacological and Parenteral Therapies"

Questions last reviewed: 18 October 2026