Safety and Infection ControlQuestion 1729 of 2368
A client takes a medication metabolized by the CYP3A4 enzyme. Which juices should the nurse advise the client to avoid?
- Regular orange juice only
- Grapefruit juice and sour orange juice
- Regular orange juice and sour orange juice
- No juices need to be avoided
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Correct answer: Grapefruit juice and sour orange juice
Grapefruit juice and sour orange juice lower CYP3A4 and raise drug blood levels. Regular orange juice had no effect.
Source: Nursing Pharmacology, 2nd edition (Open RN, Chippewa Valley Technical College, 2023), Pharmacokinetics & Pharmacodynamics: OLDER ADULT. Licensed under CC BY 4.0.
Practice the topic "Safety and Infection Control"Questions last reviewed: 18 October 2026