Pharmacological and Parenteral TherapiesQuestion 1111 of 2368

A client who received fentanyl for labor pain now has a prescription for ondansetron for nausea. Which adverse effect should the nurse monitor for?

  1. Fetal ductus arteriosus closure
  2. Liver failure from a single dose
  3. Withdrawal symptoms
  4. Serotonin syndrome
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Correct answer: Serotonin syndrome

Ondansetron can cause serotonin syndrome when combined with fentanyl, tramadol, SSRIs, SNRIs, MAOIs, or lithium.

Source: Nursing Health Promotion (Open RN, Chippewa Valley Technical College, 2025), Labor & Delivery Care: ANTIEMETICS. Licensed under CC BY 4.0.

Practice the topic "Pharmacological and Parenteral Therapies"

Questions last reviewed: 18 October 2026