Health Promotion and MaintenanceQuestion 1049 of 2368

A client's cell-free DNA screening is positive for trisomy 21. Which statement by the nurse is accurate?

  1. "This result confirms that the baby has Down syndrome."
  2. "No further testing is needed because this screening is diagnostic."
  3. "Further testing such as amniocentesis is needed to confirm a diagnosis."
  4. "This result is not valid until you repeat it after delivery."
Show answer

Correct answer: "Further testing such as amniocentesis is needed to confirm a diagnosis."

A positive cfDNA screen means the fetus is at risk. Diagnostic tests such as CVS or amniocentesis confirm the diagnosis.

Source: Nursing Health Promotion (Open RN, Chippewa Valley Technical College, 2025), Antepartum Care: Cell Free DNA (cfDNA). Licensed under CC BY 4.0.

Practice the topic "Health Promotion and Maintenance"

Questions last reviewed: 18 October 2026