RN Exam Practice
Pharmacological and Parenteral TherapiesQuestion 990 of 2368

A client with treatment-resistant depression is prescribed intranasal esketamine. Which statement by the nurse is accurate?

  1. "This medication takes 8 to 12 weeks to start working."
  2. "You will stop your oral antidepressant when you start this medication."
  3. "This medication acts quickly, and you will probably continue an oral antidepressant."
  4. "This medication is the first-line treatment for depression."
Show answer

Correct answer: "This medication acts quickly, and you will probably continue an oral antidepressant."

Esketamine usually works within a couple of hours, and clients typically continue an oral antidepressant to maintain improvement.

Source: Nursing Health Promotion (Open RN, Chippewa Valley Technical College, 2025), Mental Health Conditions: Treatments for Depression. Licensed under CC BY 4.0.

Practice the topic "Pharmacological and Parenteral Therapies"

Questions last reviewed: 18 October 2026