RN Exam Practice
Pharmacological and Parenteral TherapiesQuestion 500 of 2368

A client asks how losartan differs from an ACE inhibitor such as captopril. Which statement by the nurse is correct?

  1. Losartan blocks the conversion of angiotensin I to angiotensin II and often causes a cough.
  2. Losartan blocks angiotensin II and is not likely to cause the cough that ACE inhibitors can.
  3. Losartan increases aldosterone release and is safe in pregnancy.
  4. Losartan blocks renin release and always causes a cough.
Show answer

Correct answer: Losartan blocks angiotensin II and is not likely to cause the cough that ACE inhibitors can.

ARBs block angiotensin II directly, so they are not likely to cause the cough seen with ACE inhibitors.

Source: Nursing Pharmacology, 2nd edition (Open RN, Chippewa Valley Technical College, 2023), Cardiovascular & Renal Systems: Angiotensin II Receptor Blocker (ARB). Licensed under CC BY 4.0.

Practice the topic "Pharmacological and Parenteral Therapies"

Questions last reviewed: 18 October 2026