Pharmacological and Parenteral TherapiesQuestion 466 of 2368

A client with a severe allergy to penicillin is prescribed a cephalosporin. Which action should the nurse take before giving the drug?

  1. Give the first dose because the drugs are from different classes
  2. Give the drug with an antacid to prevent a reaction
  3. Ask the client to avoid eating until the drug is given
  4. Review the type and severity of the client's previous reaction to penicillin
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Correct answer: Review the type and severity of the client's previous reaction to penicillin

Cephalosporins and penicillins have a similar structure, so cross-sensitivity can occur.

Source: Nursing Pharmacology, 2nd edition (Open RN, Chippewa Valley Technical College, 2023), Antimicrobials: CEPHALOSPORINS. Licensed under CC BY 4.0.

Practice the topic "Pharmacological and Parenteral Therapies"

Questions last reviewed: 18 October 2026